A 34-year-old woman presents with recurrent episodes of consuming a large amount of food in a discrete period with a sense of lack of control over the past three years. She feels marked distress regarding these binge episodes and does not use compensatory behaviors like self-induced vomiting or excessive exercise. Her body mass index is 34 kg/m². Which drug is FDA-approved for this condition?

• A Fluoxetine
• B Topiramate
• C Olanzapine
• D Lisdexamfetamine ✓

Explanation

Lisdexamfetamine is the only FDA-approved medication for moderate to severe binge eating disorder. It reduces the number of binge days per week. Fluoxetine is FDA-approved for bulimia nervosa but is not the approved choice for binge eating disorder. Topiramate is effective off-label for binge eating disorder but lacks FDA approval for this indication. Olanzapine is used in anorexia nervosa to promote weight gain, not for binge eating disorder.

Reference: Kaplan and Sadock's Comprehensive Textbook of Psychiatry, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.