A 55-year-old chronic alcoholic presents with confusion, ataxia, and nystagmus. Thiamine pyrophosphate (TPP) is a cofactor for several enzymes in glucose metabolism. The ICMR-NIN 2020 RDA of thiamine for an adult Indian male (65 kg) is approximately:

• A 1.0 mg/day
• B 1.2 mg/day ✓
• C 1.8 mg/day
• D 2.4 mg/day

Explanation

The patient has Wernicke's encephalopathy. ICMR-NIN 2020 RDA for thiamine is 1.2 mg/day for adult males and 1.0 mg/day for adult females. Thiamine requirement is linked to energy intake (approximately 0.5 mg per 1000 kcal). Option A is for females, while higher values reflect therapeutic dosing rather than preventive RDA.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.