Among the forms of tuberculosis, BCG vaccination has demonstrated its best-documented and most consistent protective efficacy against:
- A Adult pulmonary tuberculosis
- B Laryngeal tuberculosis
- C Miliary tuberculosis and tuberculous meningitis in children ✓
- D Genitourinary tuberculosis
Correct answer: C. Miliary tuberculosis and tuberculous meningitis in children
Explanation
Meta-analyses show BCG is around 80 percent effective against miliary tuberculosis and tuberculous meningitis in children, which is the strongest evidence base for the vaccine and justifies giving it at birth in endemic countries. Protection against adult pulmonary disease is variable and often negligible, which explains why BCG has little impact on transmission. Disseminated childhood forms are precisely where haematogenous spread from a recent primary complex is prevented.
Reference: Park's Textbook of Preventive and Social Medicine, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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