An adult male with confirmed cholera and some dehydration is being managed in a field camp alongside ORS therapy. The preferred antibiotic regimen for him is:
- A Doxycycline 300 mg as a single dose ✓
- B Ciprofloxacin 500 mg twice daily for 5 days
- C Amoxicillin 500 mg thrice daily for 7 days
- D Metronidazole 400 mg thrice daily for 5 days
Correct answer: A. Doxycycline 300 mg as a single dose
Explanation
A single dose of doxycycline 300 mg is the drug of choice for adult cholera because it shortens diarrhoea duration, reduces vibrio excretion and has compliance advantages in outbreak settings. Ciprofloxacin faces rising resistance and needs multiple doses. Amoxicillin is less effective and metronidazole has no role since cholera is toxin-mediated rather than an invasive amoebic or anaerobic process.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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