The WHO-reduced osmolarity oral rehydration solution currently used in India contains sodium in what concentration?

• A 111 mmol/L
• B 90 mmol/L
• C 75 mmol/L ✓
• D 60 mmol/L

Explanation

The reduced osmolarity ORS has a total osmolarity of 245 mmol/L with sodium 75, glucose 75, potassium 20, chloride 65 and citrate 10 mmol/L. Earlier formulations contained sodium 90 and later 111 mmol/L with higher osmolarity, which caused more stool output and a risk of hyponatraemia-related oedema. The reduction improves efficacy and safety in non-cholera diarrhoea while retaining benefit in cholera.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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