The 'case fatality rate' (CFR) for untreated severe cholera (Cholera gravis) is approximately:
- A 1–5%
- B 10–25%
- C 25–50% ✓
- D 50–75%
Correct answer: C. 25–50%
Explanation
Without treatment, the case fatality rate of severe cholera (cholera gravis, formerly El Tor biotype) can reach 25–50% due to rapid dehydration and electrolyte loss. With prompt and adequate oral rehydration therapy (ORT) and intravenous fluids when needed, the CFR is reduced to less than 1%. This dramatic reduction illustrates the effectiveness of ORT in reducing cholera mortality.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
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