The Vi antigen polysaccharide vaccine for typhoid fever is recommended for which age group and provides protection for how long?

• A From 2 years; protection for 2 years
• B From 5 years; protection for 5 years
• C From 6 months; protection for 1 year
• D From 2 years; protection for 3 years ✓

Explanation

The Vi capsular polysaccharide typhoid vaccine is recommended from 2 years of age and requires a single intramuscular injection. It provides approximately 50–80% protection for about 3 years. It is a T-independent antigen (polysaccharide) and thus does not work under 2 years. The Ty21a oral live attenuated vaccine is used from 6 years; typhoid conjugate vaccine (TCV) can be given from 6 months.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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