A 28-year-old man presents with fever, headache and petechiae. Dengue NS1 antigen is positive on day 2 of fever. His platelet count is 85,000/µL. The MOST appropriate management at this stage is:
- A Immediate prophylactic platelet transfusion
- B IV fluid resuscitation with colloids
- C Oral hydration, paracetamol, monitoring for warning signs ✓
- D Aspirin for fever and pain relief
Correct answer: C. Oral hydration, paracetamol, monitoring for warning signs
Explanation
This patient has probable dengue fever without severe dengue warning signs (vomiting, abdominal pain, rapid clinical deterioration, bleeding from mucosae, lethargy, liver enlargement >2 cm, haematocrit rise with platelet drop <20,000). WHO guidelines recommend outpatient management with oral hydration, paracetamol, and close monitoring in dengue without warning signs. Aspirin is contraindicated due to bleeding risk. Platelet transfusion is reserved for platelets <10,000/µL or active significant bleeding.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.