Community Medicine (PSM) · Communicable Diseases (Malaria, Tuberculosis, Dengue, Polio, Hepatitis, Cholera)

Vibrio cholerae O139 Bengal differs from O1 El Tor in that it:

  • A Does not produce cholera toxin
  • B Possesses a capsule providing serum resistance and is not agglutinated by O1 antiserum
  • C Is more common in freshwater environments
  • D Is susceptible to standard O1 vaccines
Correct answer: B. Possesses a capsule providing serum resistance and is not agglutinated by O1 antiserum

Explanation

V. cholerae O139 Bengal emerged in 1992 in India and Bangladesh as the only non-O1 serogroup to cause epidemic cholera. Its key distinguishing feature is the presence of a polysaccharide capsule (encoded by a genomic island absent in O1) conferring serum resistance and preventing agglutination by O1 antiserum. Existing O1 vaccines do not protect against O139 because of the different O-antigen.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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