Physiology · Temperature Regulation and Body Fluid Compartments

A neonate in the delivery room is at high risk for hypothermia. Which anatomical and physiological characteristic MOST predisposes the newborn to rapid heat loss compared to adults?

  • A Inability to shiver
  • B Higher surface-area-to-body-mass ratio
  • C Absent brown adipose tissue
  • D Overactive sweat glands
Correct answer: B. Higher surface-area-to-body-mass ratio

Explanation

Neonates have a substantially higher surface-area-to-body-mass ratio than adults, which increases heat loss by radiation, convection, and evaporation. This is the single greatest predisposing factor. Newborns do have brown adipose tissue for non-shivering thermogenesis and cannot shiver effectively, but the surface area ratio is the dominant contributor to heat loss. Neonatal sweat glands are immature, not overactive.

Reference: Guyton and Hall Textbook of Medical Physiology, 14th ed.

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