Physiology · Pregnancy, Fetal and Neonatal Physiology

A term neonate is delivered and placed under a radiant warmer. The primary mechanism by which a neonate generates heat in the immediate postnatal period is:

  • A Non-shivering thermogenesis in brown adipose tissue
  • B Shivering thermogenesis in skeletal muscle
  • C Metabolism of white adipose tissue triglycerides
  • D Peripheral vasoconstriction reducing heat loss
Correct answer: A. Non-shivering thermogenesis in brown adipose tissue

Explanation

Neonates rely on non-shivering thermogenesis in brown adipose tissue, which is rich in mitochondria and uncoupling protein 1 (thermogenin). Shivering thermogenesis is minimal or absent in neonates. White fat stores energy but does not generate heat directly. Peripheral vasoconstriction reduces heat loss but does not generate heat; it is a conservation mechanism, not a production mechanism.

Reference: Nelson Textbook of Pediatrics, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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