Physiology · Pregnancy, Fetal and Neonatal Physiology

In the fetal circulation, which structure allows oxygenated blood from the umbilical vein to bypass the hepatic sinusoids and enter the inferior vena cava directly?

  • A Ductus venosus
  • B Foramen ovale
  • C Ductus arteriosus
  • D Umbilical arteriovenous anastomosis
Correct answer: A. Ductus venosus

Explanation

The ductus venosus is a fetal vascular shunt connecting the left branch of the portal vein directly to the inferior vena cava, allowing oxygenated blood from the umbilical vein to bypass about 50% of hepatic circulation. This preferentially delivers well-oxygenated blood towards the right heart and foramen ovale. After birth, the ductus venosus closes functionally within hours and anatomically within 1–3 weeks, becoming the ligamentum venosum.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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