Physiology · Neurophysiology (Synapse, Action Potential, Tracts, Reflexes)

A patient with a spinal cord lesion at T10 has loss of pain and temperature sensation on the contralateral side beginning 2 segments below the lesion, with preserved ipsilateral proprioception. Which tract is damaged?

  • A Contralateral lateral spinothalamic tract
  • B Ipsilateral posterior column (dorsal column — medial lemniscus pathway)
  • C Contralateral anterior corticospinal tract
  • D Ipsilateral lateral spinothalamic tract (anterolateral system)
Correct answer: A. Contralateral lateral spinothalamic tract

Explanation

Pain and temperature fibres (first-order neurons) enter the spinal cord ipsilaterally, ascend 1–2 segments in Lissauer's tract, then synapse in the dorsal horn (Rexed laminae I, II, V). Second-order neurons immediately decussate via the anterior commissure and ascend in the contralateral anterolateral (lateral spinothalamic) tract. Therefore, a unilateral lesion of the lateral spinothalamic tract causes contralateral pain/temperature loss beginning 2 segments below the level of the lesion (accounting for the ascent in Lissauer's tract before decussation). The preserved ipsilateral proprioception confirms the posterior column is intact on that side.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

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