Physiology · Neurophysiology (Synapse, Action Potential, Tracts, Reflexes)

A patient has damage to the lateral corticospinal tract at C5 on the right side. Which pattern of deficits would be expected?

  • A Contralateral UMN signs below C5 AND contralateral loss of all sensory modalities below C5
  • B Ipsilateral LMN signs at C5 level with no sensory loss
  • C Ipsilateral UMN signs below C5 AND ipsilateral loss of fine touch and proprioception below C5 AND contralateral loss of pain and temperature below C5
  • D Bilateral UMN signs and bilateral sensory loss below C5
Correct answer: C. Ipsilateral UMN signs below C5 AND ipsilateral loss of fine touch and proprioception below C5 AND contralateral loss of pain and temperature below C5

Explanation

Right lateral C5 cord damage produces Brown-Séquard syndrome: (1) Ipsilateral (right) UMN signs below C5 — lateral corticospinal tract is already crossed; (2) Ipsilateral (right) loss of tactile discrimination, vibration, and proprioception — dorsal column is ipsilateral; (3) Contralateral (left) loss of pain and temperature from below C5 — spinothalamic tract has already crossed 1–2 segments above its entry level. LMN signs would occur at the level of injury (C5 segment) ipsilaterally due to anterior horn damage.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

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