ADH (vasopressin) is synthesized as part of a larger precursor molecule that includes a carrier protein. The carrier protein for ADH is called:

• A Neurophysin I
• B Copeptin
• C Preprovasophysin
• D Neurophysin II ✓

Explanation

The ADH precursor (prepropressophysin) is cleaved into ADH, neurophysin II, and copeptin. Neurophysin II specifically binds and stabilizes ADH during axonal transport. Neurophysin I is the carrier for oxytocin. Copeptin is the C-terminal glycopeptide released in equimolar amounts with ADH and is used as a stable surrogate marker.

Reference: Ganong's Review of Medical Physiology, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.