In the male reproductive axis, Sertoli cells produce inhibin B in response to FSH. The primary action of inhibin B is to provide negative feedback on which pituitary hormone?
- A LH
- B FSH ✓
- C Prolactin
- D GH
Correct answer: B. FSH
Explanation
Inhibin selectively suppresses FSH secretion from anterior pituitary gonadotrophs through negative feedback. In males, Sertoli cells produce inhibin B in response to FSH, and inhibin B feeds back to inhibit FSH. In females, granulosa cells produce inhibin A and B. LH is regulated primarily by gonadal steroids, not inhibin.
Reference: Ganong's Review of Medical Physiology, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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