Somatostatin inhibits growth hormone secretion from the anterior pituitary. The hypothalamic nucleus that is the major source of somatostatin regulating GH secretion is the:
- A Periventricular nucleus ✓
- B Arcuate nucleus
- C Paraventricular nucleus
- D Suprachiasmatic nucleus
Correct answer: A. Periventricular nucleus
Explanation
Somatostatin neurons regulating GH secretion are concentrated in the periventricular nucleus of the hypothalamus. These neurons project to the median eminence and release somatostatin into the hypophyseal portal system. The paraventricular nucleus contains CRH and TRH neurons, while the arcuate nucleus contains GHRH and dopamine neurons.
Reference: Ganong's Review of Medical Physiology, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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