Which pancreatic islet product is co-secreted with insulin by beta cells and slows gastric emptying while suppressing postprandial glucagon release?
- A Pancreatic polypeptide
- B Somatostatin
- C Amylin ✓
- D Ghrelin
Correct answer: C. Amylin
Explanation
Amylin is stored in beta cell granules and cosecreted with insulin in response to nutrients. It complements insulin by delaying gastric emptying, suppressing inappropriate postprandial glucagon secretion, and promoting satiety via the area postrema. Its synthetic analogue pramlintide is used adjunctively in diabetes. Somatostatin comes from delta cells and broadly inhibits all islet hormones, while ghrelin is gastric in origin and orexigenic.
Reference: Ganong Review of Medical Physiology, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.