Physiology · Cardiac Physiology (Cycle, Output, ECG, Electrophysiology)

A 45-year-old hypertensive patient undergoes valsalva maneuver. In phase II of the Valsalva maneuver, which hemodynamic change occurs?

  • A Increased intrathoracic pressure augments venous return → increased cardiac output → reflex bradycardia
  • B Blood pressure rises acutely and remains elevated throughout phase II
  • C Increased intrathoracic pressure reduces venous return → fall in cardiac output → reflex tachycardia and vasoconstriction
  • D Heart rate falls due to direct compression of the SA node during bearing down
Correct answer: C. Increased intrathoracic pressure reduces venous return → fall in cardiac output → reflex tachycardia and vasoconstriction

Explanation

Phase II of the Valsalva maneuver (sustained strain): elevated intrathoracic pressure impedes venous return to the right heart, reducing preload and cardiac output, causing blood pressure to fall. The baroreceptor reflex is activated → sympathetic stimulation → reflex tachycardia, increased myocardial contractility, and peripheral vasoconstriction. In phase II late, blood pressure begins to recover toward baseline due to vasoconstriction. Phase IV (after release): venous return suddenly restored → overshoot hypertension → reflex bradycardia. Absence of this square-wave response in heart failure patients (fixed output) aids diagnosis.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

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