Physiology · Cardiac Physiology (Cycle, Output, ECG, Electrophysiology)

During which phase of the cardiac cycle is the velocity of blood flow across the aortic valve the HIGHEST?

  • A Isovolumetric contraction
  • B Reduced ejection phase (last two-thirds of systole)
  • C Rapid ejection phase (early systole, first third of ejection)
  • D Isovolumetric relaxation
Correct answer: C. Rapid ejection phase (early systole, first third of ejection)

Explanation

After aortic valve opening, rapid ejection (early systolic ejection, first ~30% of ejection time) accounts for approximately 70% of stroke volume and produces peak aortic flow velocity (~100 cm/s). The aortic valve closes during the reduced ejection phase, when flow is decelerating. Isovolumetric contraction and relaxation are closed-valve periods with no aortic flow. This physiological peak flow velocity is the basis for peak flow measurements by echocardiographic Doppler to estimate aortic valve gradients.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

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