Physiology · Autonomic Nervous System Physiology — Integrated

Which of the following is the ONLY organ that receives ONLY sympathetic innervation (no parasympathetic supply) from the ANS?

  • A Heart (SA node)
  • B Adrenal medulla
  • C Parotid salivary gland
  • D Blood vessels (systemic arterioles)
Correct answer: D. Blood vessels (systemic arterioles)

Explanation

Most systemic arterioles and veins receive only sympathetic (adrenergic) innervation and have no parasympathetic supply. Vasoconstriction occurs via alpha-1 receptors; vasodilation in some vascular beds (e.g., skeletal muscle) is via beta-2 receptors or cholinergic sympathetic fibers. The heart receives both sympathetic (accelerator) and parasympathetic (vagal) innervation. The adrenal medulla receives preganglionic sympathetic fibers but this is a ganglion, not an effector organ per se. Salivary glands receive both autonomic divisions.

Reference: Guyton & Hall, Textbook of Medical Physiology, 14th ed.

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