A 72-year-old man with hypertension and symptomatic benign prostatic hyperplasia (BPH) requires an antihypertensive that also improves urinary symptoms. Which drug is best suited?
- A Amlodipine
- B Atenolol
- C Prazosin ✓
- D Hydrochlorothiazide
Correct answer: C. Prazosin
Explanation
Alpha-1 blockers like prazosin relax smooth muscle in the prostate and bladder neck, relieving bladder outlet obstruction in BPH, while also lowering blood pressure. Beta-blockers, calcium channel blockers, and thiazides do not improve urinary symptoms.
Reference: Katzung's Basic & Clinical Pharmacology, 15th ed.
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