Pharmacology · Cardiovascular Drugs (Antihypertensives, Anti-Anginals, Heart Failure, Anti-Arrhythmics)

A patient with permanent atrial fibrillation and a resting ventricular rate of 130 bpm is not a candidate for beta-blockers due to severe asthma. Which calcium channel blocker is preferred for rate control?

  • A Amlodipine
  • B Diltiazem
  • C Nifedipine
  • D Nicardipine
Correct answer: B. Diltiazem

Explanation

Diltiazem (a non-dihydropyridine calcium channel blocker) slows AV-nodal conduction and is first-line for rate control in AF when beta-blockers are contraindicated, as in severe asthma. Amlodipine and nifedipine are dihydropyridines with minimal AV-nodal effect and are used for hypertension, not rate control. Diltiazem and verapamil are the non-DHP CCBs used for this purpose.

Reference: Katzung Basic and Clinical Pharmacology, 15th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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