Pilocarpine is used in acute angle-closure glaucoma. The miosis it produces facilitates drainage of aqueous humor through which anatomical structure?

• A Canal of Schlemm
• B Uveoscleral pathway
• C Suprachoroidal space
• D Trabecular meshwork ✓

Explanation

Pilocarpine stimulates M3 receptors on the pupillary sphincter, causing miosis that pulls the iris away from the trabecular meshwork, opening the drainage angle and facilitating aqueous humor outflow through the trabecular meshwork into the canal of Schlemm. The trabecular meshwork is the primary conventional drainage pathway that is obstructed in angle-closure glaucoma.

Reference: Katzung Basic and Clinical Pharmacology, 15th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.