A 65-year-old man with open-angle glaucoma is prescribed a topical beta-blocker. Which topical beta-blocker is most commonly used and reduces aqueous humor production without causing corneal anesthesia?

• A Betaxolol
• B Levobunolol
• C Carteolol
• D Timolol ✓

Explanation

Timolol is the most widely used topical beta-blocker for glaucoma. It reduces aqueous humor production by blocking beta-2 receptors in the ciliary epithelium. Unlike some other topical beta-blockers, it lacks membrane-stabilizing activity and does not cause corneal anesthesia, which is a safety advantage for long-term use.

Reference: Katzung Basic and Clinical Pharmacology, 15th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.