Which fluoroquinolone is considered 'respiratory quinolone' due to its enhanced activity against Streptococcus pneumoniae and atypical organisms, making it useful in community-acquired pneumonia?
- A Ciprofloxacin
- B Norfloxacin
- C Ofloxacin
- D Moxifloxacin ✓
Correct answer: D. Moxifloxacin
Explanation
Moxifloxacin (and levofloxacin) are called respiratory quinolones because of their potent activity against Streptococcus pneumoniae (gram-positive), atypicals (Mycoplasma, Chlamydophila, Legionella), and gram-negatives. Ciprofloxacin has poor anti-pneumococcal activity. Norfloxacin is primarily used for urinary tract infections and has limited systemic bioavailability.
Reference: KD Tripathi, Essentials of Medical Pharmacology, 8th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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