A 30-year-old woman with type 1 diabetes is planning pregnancy. She uses insulin aspart with meals and insulin detemir as basal. The target fasting plasma glucose in the first trimester of pregnancy for diabetic women according to standard guidelines is:

• A Less than 120 mg/dL
• B Less than 95 mg/dL ✓
• C Less than 140 mg/dL
• D Less than 80 mg/dL

Explanation

The American Diabetes Association recommends a fasting plasma glucose target of less than 95 mg/dL in pregnant women with pregestational diabetes (both type 1 and type 2), with 1-hour postprandial less than 140 mg/dL and 2-hour postprandial less than 120 mg/dL. Tighter targets reduce the risk of congenital anomalies and macrosomia. Indian guidelines follow similar targets.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.