A 35-year-old woman with type 1 diabetes notices lumpy, hardened areas at her insulin injection sites. She has been injecting insulin into the same areas for convenience. What is the recommended strategy to prevent this complication?

• A Switch from analog insulin to human insulin
• B Rotate injection sites systematically across different anatomical regions ✓
• C Apply topical corticosteroids to affected areas
• D Switch to an insulin pump using only one site

Explanation

Lipohypertrophy results from repeated injection into the same site and is prevented by systematic site rotation across abdomen, thighs, arms, and buttocks. Switching insulin type (A) does not prevent it. Topical steroids (C) are not indicated. Insulin pumps (D) still require site rotation every 48-72 hours to prevent lipohypertrophy and infection.

Reference: Williams Textbook of Endocrinology, 14th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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