Which aminoglycoside remains the drug of choice for tularemia and is used parenterally for plague?
- A Amikacin
- B Tobramycin
- C Streptomycin ✓
- D Netilmicin
Correct answer: C. Streptomycin
Explanation
Streptomycin, the first aminoglycoside discovered, retains first-line status for tularemia caused by Francisella tularensis and is an accepted injectable agent for Yersinia pestis (plague). It is also part of the retreatment regimen for tuberculosis. Amikacin and tobramycin are reserved mainly for severe aerobic Gram-negative bacillary infections and are not preferred for these intracellular zoonoses. Netilmicin has largely fallen out of use and offers no advantage here.
Reference: Katzung's Basic and Clinical Pharmacology, 15th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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