Pharmacology · Anti-Mycobacterial Drugs (Anti-TB, Anti-Leprosy)

According to WHO multidrug therapy guidelines, a patient classified as paucibacillary leprosy receives rifampicin once monthly under supervision plus daily self-administered dapsone. What is the minimum duration of this regimen?

  • A 24 months
  • B 12 months
  • C 6 months
  • D 3 months
Correct answer: C. 6 months

Explanation

Paucibacillary leprosy (1 to 5 skin lesions, negative skin smears) is treated with monthly supervised rifampicin plus daily dapsone for a minimum of 6 months. Multibacillary disease requires the addition of clofazimine and a minimum of 12 months. Confusing the 6-month paucibacillary duration with the 12-month multibacillary duration is the common error tested here.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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