Pediatrics · Pediatric Rheumatology and Musculoskeletal Disorders

Which category of juvenile idiopathic arthritis carries the highest risk of asymptomatic chronic anterior uveitis requiring routine slit lamp screening?

  • A RF-positive polyarticular JIA
  • B Early-onset oligoarticular JIA in an ANA-positive girl
  • C Systemic JIA with quotidian fever
  • D Enthesitis-related arthritis in an HLA-B27 positive boy
Correct answer: B. Early-onset oligoarticular JIA in an ANA-positive girl

Explanation

Young age at onset, female sex, ANA positivity, and oligoarticular disease define the classic high-risk group for insidious, painless chronic anterior uveitis that can cause band keratopathy, synechiae, and blindness if unscreened. HLA-A27 boys do get acute symptomatic anterior uveitis, but it is painful and red, so it does not drive the same silent screening protocol as ANA-positive oligoarticular girls.

Reference: Nelson Textbook of Pediatrics, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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