Which category of juvenile idiopathic arthritis carries the highest risk of asymptomatic chronic anterior uveitis requiring routine slit lamp screening?
- A RF-positive polyarticular JIA
- B Early-onset oligoarticular JIA in an ANA-positive girl ✓
- C Systemic JIA with quotidian fever
- D Enthesitis-related arthritis in an HLA-B27 positive boy
Explanation
Young age at onset, female sex, ANA positivity, and oligoarticular disease define the classic high-risk group for insidious, painless chronic anterior uveitis that can cause band keratopathy, synechiae, and blindness if unscreened. HLA-A27 boys do get acute symptomatic anterior uveitis, but it is painful and red, so it does not drive the same silent screening protocol as ANA-positive oligoarticular girls.
Reference: Nelson Textbook of Pediatrics, 21st ed.
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