A term neonate is diagnosed with physiological jaundice on day 3. The total serum bilirubin is 11 mg/dL. Which of the following features distinguishes physiological jaundice from pathological jaundice?
- A Jaundice appearing within 24 hours of life
- B Total bilirubin rising by more than 5 mg/dL per day
- C Peak bilirubin not exceeding 12.9 mg/dL in term infants ✓
- D Conjugated bilirubin greater than 2 mg/dL
Correct answer: C. Peak bilirubin not exceeding 12.9 mg/dL in term infants
Explanation
Physiological jaundice in term neonates peaks at no more than 12.9 mg/dL, appears after 24 hours, and the bilirubin rise is less than 5 mg/dL per day. Jaundice within 24 hours, a rise exceeding 5 mg/dL per day, or conjugated bilirubin greater than 2 mg/dL are all features of pathological jaundice requiring investigation.
Reference: Nelson Textbook of Pediatrics, 21st ed.
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