A 5-week-old infant being evaluated for suspected congenital syphilis undergoes long bone radiographs. The report describes bilateral metaphyseal lucent bands with destruction of the medial proximal tibial metaphysis, along with periosteal reaction. The limb movements are reduced and the infant cries when handled. Which eponym corresponds to the tibial finding described?

• A Hutchinson sign
• B Wimberger sign ✓
• C Sabin sign
• D Koplik sign

Explanation

Congenital syphilis produces osteochondritis and periostitis of long bones, classically with symmetric metaphyseal lucent bands. Destruction of the medial aspect of the proximal tibial metaphysis is the Wimberger sign, a characteristic radiographic marker. The associated painful bones produce pseudoparalysis of Parrot. Hutchinson sign refers to peg-shaped centrally notched incisor teeth, a late stigmata appearing after eruption of permanent teeth, and Koplik sign belongs to measles.

Reference: Nelson Textbook of Pediatrics, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.