Pediatrics · Neonatal Sepsis, TORCH and Perinatal Infections

Radiographs of a 6-week-old infant being evaluated for congenital syphilis show bilateral metaphyseal lucent bands, osteochondritis, and a destructive lesion of the medial proximal tibia. What is the eponym for the tibial lesion?

  • A Saber shins
  • B Hutchinson sign
  • C Moon molars
  • D Wimberger sign
Correct answer: D. Wimberger sign

Explanation

Wimberger sign is destruction of the medial aspect of the proximal tibial metaphysis seen in early congenital syphilis, along with metaphyseal lucent bands and osteochondritis of long bones. Hutchinson teeth, moon molars, interstitial keratitis and saber shins are stigmata of LATE congenital syphilis appearing after 2 years of age, so they are incorrect for a 6-week-old infant. Long bone changes are present in a majority of symptomatic congenital syphilis cases.

Reference: Nelson Textbook of Pediatrics, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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