Pediatrics · CNS Disorders in Children (Seizures, Hydrocephalus, Meningitis)

A 3-week-old male infant presents with projectile non-bilious vomiting after feeds for the past 7 days. He appears hungry after vomiting. On examination, a hard olive-shaped mass is palpable in the right epigastrium. Blood gases show: pH 7.55, pCO2 48 mmHg, bicarbonate 38 mEq/L, chloride 85 mEq/L, potassium 2.8 mEq/L. What is the CORRECT management sequence?

  • A Emergency surgical pyloromyotomy (Ramstedt's) immediately
  • B IV dextrose saline without KCl, then pyloromyotomy
  • C Endoscopic balloon dilation of pylorus
  • D IV normal saline + KCl replacement to correct metabolic alkalosis, THEN elective pyloromyotomy
Correct answer: D. IV normal saline + KCl replacement to correct metabolic alkalosis, THEN elective pyloromyotomy

Explanation

Hypertrophic pyloric stenosis presents with hypochloremic, hypokalemic metabolic alkalosis (paradoxical aciduria) due to loss of HCl in vomitus and renal compensatory H+ wasting. Surgery (Ramstedt's pyloromyotomy) is NEVER an emergency — it is a medical emergency to correct the metabolic alkalosis first. IV normal saline corrects dehydration and chloride depletion; KCl supplementation corrects hypokalemia. Pyloromyotomy is performed only after metabolic correction (bicarbonate <30 mEq/L, chloride >100 mEq/L, urine output adequate). Premature surgery under alkalotic conditions carries anesthesia risk (apnea).

Reference: Ghai Essential Pediatrics, 10th ed.

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