Takayasu arteritis affects large vessels (aorta and its branches) in young women. It is classified as a vasculitis affecting which size of vessels?

• A Small vessel vasculitis
• B Medium vessel vasculitis
• C Variable vessel vasculitis
• D Large vessel vasculitis ✓

Explanation

Takayasu arteritis is a large vessel vasculitis (affecting the aorta and its major branches) and is classified alongside giant cell arteritis in the 2012 Chapel Hill Consensus Criteria nomenclature. It causes granulomatous inflammation of the aortic wall, leading to stenosis, occlusion, or aneurysm. Medium vessel vasculitis includes polyarteritis nodosa and Kawasaki disease; small vessel vasculitis includes ANCA-associated vasculitides.

Reference: Robbins & Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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