A patient with hemophilia A has factor VIII activity measured at 0.5% of normal. According to standard classification, this patient's disease severity is categorized as:

• A Mild hemophilia A
• B Moderate hemophilia A
• C Subclinical hemophilia A
• D Severe hemophilia A ✓

Explanation

Hemophilia A severity is classified by baseline factor VIII activity: severe is <1% (0.01 IU/mL), moderate is 1-5%, and mild is 5-40% of normal. At 0.5%, this patient has severe disease, characterized by spontaneous bleeding into joints and muscles. Mild hemophilia typically bleeds only with surgery or trauma. This classification guides prophylactic treatment decisions.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.