During autopsy, a 70-year-old man is found to have a small focus of normal pancreatic tissue embedded in the wall of his stomach. This lesion is best classified as:
- A Hamartoma
- B Choristoma ✓
- C Teratoma
- D Metaplasia
Correct answer: B. Choristoma
Explanation
A choristoma is a heterotopic rest of normally organized tissue located at an abnormal site, such as pancreatic tissue in the stomach or gastric mucosa in a Meckel diverticulum. A hamartoma is disorganized overgrowth of tissue indigenous to the site, such as a Peutz-Jeghers polyp. Teratomas contain derivatives of multiple germ layers arising from totipotent cells, and metaplasia is a reversible change of one differentiated tissue into another within the same site.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.