Pathology · Neoplasia (Classification, Carcinogenesis, Tumor Markers, Paraneoplastic)

During routine histology of a resected Meckel diverticulum, a focus of gastric mucosa is identified within the ileal wall. This finding is correctly classified as:

  • A Hamartoma
  • B Choristoma
  • C Teratoma
  • D Metaplasia
Correct answer: B. Choristoma

Explanation

A choristoma (heterotopic rest) is normal mature tissue located at a site where it does not belong, such as gastric mucosa in the ileum of a Meckel diverticulum or pancreatic tissue in the stomach wall. A hamartoma (option A) is disorganized but native overgrowth of tissue indigenous to the site, for example a Peutz-Jeghers polyp. Metaplasia is an adaptive change of resident tissue, not ectopic rests, which rules out option D.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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