A 60-year-old man with newly diagnosed pancreatic adenocarcinoma develops recurrent, migratory superficial thrombophlebitis in his arms and chest wall. This paraneoplastic phenomenon is known as:
- A Sweet syndrome
- B Lambert-Eaton syndrome
- C Stiff-person syndrome
- D Trousseau syndrome ✓
Explanation
Trousseau syndrome is a paraneoplastic hypercoagulable state presenting as migratory thrombophlebitis, classically associated with pancreatic and lung adenocarcinomas. Lambert-Eaton syndrome is associated with small cell lung carcinoma and causes muscle weakness. Sweet syndrome is febrile neutrophilic dermatosis. Stiff-person syndrome is associated with anti-amphiphysin antibodies.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.