CA 19-9 is a sialylated Lewis blood group antigen used as a tumor marker. It is most frequently elevated in which malignancy?
- A Gastric adenocarcinoma
- B Hepatocellular carcinoma
- C Pancreatic ductal adenocarcinoma ✓
- D Ovarian carcinoma
Correct answer: C. Pancreatic ductal adenocarcinoma
Explanation
CA 19-9 is elevated in 70 to 90 percent of pancreatic ductal adenocarcinomas and is the most widely used marker for diagnosis and monitoring this malignancy. It can also be elevated in cholangiocarcinoma and colorectal cancer. AFP is the primary marker for hepatocellular carcinoma. CA-125 is the primary marker for ovarian carcinoma. CEA is the marker for colorectal carcinoma.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.