Pathology · Neoplasia (Classification, Carcinogenesis, Tumor Markers, Paraneoplastic)

A resected segment of ileum in a child with a Meckel diverticulum shows islands of gastric fundic-type mucosa within the diverticular wall. This finding represents which entity?

  • A Hamartoma
  • B Choristoma
  • C Teratoma
  • D Metaplasia
Correct answer: B. Choristoma

Explanation

A choristoma is a heterotopic rest of normal tissue located at a site where it does not normally occur, such as gastric mucosa in the ileum or pancreas in the wall of the stomach. A hamartoma, by contrast, is a disorganized overgrowth of mature cells indigenous to the site, such as a Peutz-Jeghers polyp. Because gastric mucosa is not native to ileum, choristoma is the correct classification, ruling out option A.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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