A biopsy of a lung lesion shows a disorganized but mature mixture of cartilage, smooth muscle, and adipose tissue. The lesion is present since birth and has grown slowly with the patient. Which term best describes this lesion?
- A Choristoma
- B Teratoma
- C Hamartoma ✓
- D Hamartomatous polyp
Correct answer: C. Hamartoma
Explanation
A hamartoma is a disorganized overgrowth of mature tissues indigenous to the site, here all three components are native to lung. A choristoma is normal tissue located at an ectopic site, such as gastric mucosa in the esophagus, which kills option A. A teratoma contains derivatives of more than one germ cell layer, typically all three, and is a true neoplasm of germ cells rather than a malformative growth.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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