Pathology · Lung Pathology (Obstructive, Restrictive, Tumors, Infections)

A 5-year-old child presents with chronic cough, recurrent pneumonia in the same location, and failure to thrive. CT chest shows a solid mass with systemic arterial supply from the aorta. What is the diagnosis?

  • A Bronchogenic cyst
  • B Pulmonary sequestration
  • C Congenital lobar emphysema
  • D Pulmonary interstitial emphysema
Correct answer: B. Pulmonary sequestration

Explanation

Pulmonary sequestration is a congenital malformation where a nonfunctioning lung mass receives systemic arterial blood supply (usually from the aorta), not pulmonary circulation. It predisposes to recurrent infections. Bronchogenic cyst is a mediastinal cystic lesion without systemic arterial supply. Congenital lobar emphysema presents with respiratory distress in infancy due to overinflation.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

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