Pathology · CNS Pathology (Tumors, Degenerative, Infections)

A 4-year-old child presents with hydrocephalus. MRI shows a fourth ventricular tumor. Histology demonstrates perivascular pseudorosettes. Which variant of this tumor is most common in the spinal cord of adults?

  • A Subependymoma
  • B Myxopapillary ependymoma
  • C Papillary ependymoma
  • D Clear cell ependymoma
Correct answer: B. Myxopapillary ependymoma

Explanation

The tumor is ependymoma. Myxopapillary ependymoma is a grade 1 variant that arises in the conus medullaris and cauda equina of adults. Subependymomas are benign and often incidental. Perivascular pseudorosettes are a hallmark of ependymomas, distinguishing them from other gliomas.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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