Pathology · CNS Pathology (Tumors, Degenerative, Infections)

A 55-year-old woman presents with chronic headaches and visual disturbances. MRI shows a well-circumscribed, dural-based mass attached to the falx cerebri. Histology shows whorled arrays of meningothelial cells with numerous laminated calcifications. What are these calcified structures called?

  • A Psammoma bodies
  • B Verocay bodies
  • C Rosenthal fibers
  • D Hyaline arteriolosclerosis
Correct answer: A. Psammoma bodies

Explanation

The dural-based mass is a meningioma. It characteristically shows whorled meningothelial cells and psammoma bodies, which are laminated calcifications. Verocay bodies are seen in schwannomas, Rosenthal fibers are seen in pilocytic astrocytomas, and hyaline arteriolosclerosis is a vascular change in hypertension.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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