Pathology · CNS Pathology (Tumors, Degenerative, Infections)

A 40-year-old woman presents with unilateral sensorineural hearing loss and tinnitus. MRI shows a cerebellopontine angle mass extending into the internal auditory canal. Histology shows alternating hypercellular and hypocellular areas with nuclear palisading. What are the hypocellular, myxoid areas called?

  • A Antoni A areas
  • B Antoni B areas
  • C Verocay bodies
  • D Psammoma bodies
Correct answer: B. Antoni B areas

Explanation

The cerebellopontine angle mass is a schwannoma. It characteristically shows Antoni A areas, which are hypercellular with palisading nuclei forming Verocay bodies, and Antoni B areas, which are hypocellular and loosely arranged in a myxoid stroma. Psammoma bodies are seen in meningiomas.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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