A 55-year-old woman with long-standing uncontrolled hypertension presents with papilledema and renal failure. Renal biopsy shows bright eosinophilic deposits in the walls of arterioles with smooth muscle cell necrosis. Which type of necrosis is demonstrated?
- A Fibrinoid necrosis ✓
- B Caseous necrosis
- C Fat necrosis
- D Gummatous necrosis
Correct answer: A. Fibrinoid necrosis
Explanation
Fibrinoid necrosis is seen in malignant hypertension and vasculitides. It results from plasma protein leakage into vessel walls damaged by endothelial injury, producing bright eosinophilic deposits. Caseous necrosis is seen in tuberculosis. Fat necrosis occurs in acute pancreatitis. Gummatous necrosis is seen in tertiary syphilis.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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