Caseous necrosis characteristically differs from coagulative necrosis because it shows:

• A Preserved cellular outlines with loss of nuclei
• B Amorphous pink deposition in vessel walls with luminal narrowing
• C Neutrophil-rich liquid pus with complete digestion of tissue
• D Complete destruction of architecture replaced by granular amorphous debris within granulomas ✓

Explanation

In caseous necrosis, typical of tuberculosis, the tissue architecture is completely obliterated and replaced by granular, amorphous, eosinophilic debris enclosed within granulomatous inflammation. Coagulative necrosis (option A) preserves cellular and architectural outlines for days. Option C describes liquefactive necrosis of abscesses. Option B describes fibrinoid necrosis of vessel walls. Recognizing that caseous necrosis combines features of both coagulative and liquefactive patterns with total architecture loss is the discriminating point.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.