Which coronary artery is most commonly occluded in fatal transmural myocardial infarction?
- A Left anterior descending artery ✓
- B Left circumflex artery
- C Right coronary artery
- D Left main trunk
Correct answer: A. Left anterior descending artery
Explanation
The LAD supplies the anterior wall, apex, and anterior two thirds of the interventricular septum, and its proximal segment bears the greatest hemodynamic stress from atherosclerosis, making it the most frequent site of occlusive thrombus. The RCA and left circumflex are next in frequency; isolated left main disease causes massive infarction but is far less common as the culprit vessel.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
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Written and medically reviewed by the StethoPrep medical team.